1. Structural characteristics
Mpeg-ha is formed by linking methoxy polyethylene glycol (mPEG) with Hexanoic Acid. In the mPEG-HA molecule, the PEG portion and the carboxyl group (COOH) are connected by an amyl (CH2ch2ch2ch2ch2ch2ch2) bond.
2. Functional group analysis
mPEG-HA as a PEG derivative, its functional groups mainly include:
Methoxy (-OCH3) :
The methoxy group is located at the end of the PEG chain, giving mPEG-HA certain chemical stability and reactivity.
The presence of methoxy also affects the water solubility and biocompatibility of mPEG-HA.
Polyethylene glycol chain (-PEG-) :
Polyethylene glycol chain is the main component of mPEG-HA, which has excellent hydrophilicity and flexibility.
The PEGylated chain can reduce the stimulation response of biological tissues and improve the biocompatibility of mPEG-HA.
The flexibility of the polyethylene glycol chain enables mPEG-HA to show good adaptability in different chemical environments.
Carboxyl group (-COOH) :
The carboxyl group is another important functional group of mPEG-HA, which is acidic and can participate in a variety of chemical reactions.
The existence of carboxyl group enables mPEG-HA to react with other compounds, such as coupling and crosslinking, and further expand its application field.
Carboxyl groups can also form complexes with metal ions, giving mPEG-HA more functional properties.
3. molecular weight and customization
The molecular weight of mPEG-HA can be customized to suit your needs. Common molecular weight specifications include 200, 400, 1K (1000), 2K (2000), 3.4K (3400), 5K (5000), 6K (6000), 10K (10000), 20K (20000), 30K (30000), and 40K (40000). These different molecular weights of mPEG-HA provide a rich choice for scientific experiments.
4. Application field
Because of its unique structure and functional group properties, mPEG-HA has shown a wide range of application prospects in many fields:
Drug delivery: mPEG-HA has good biocompatibility and degradability, and is often used as a drug carrier or stabilizer to improve the stability and targeting of drugs.
Research on new nano materials: mPEG-HA can be used as a surface modifier to improve the stability and biocompatibility of nanomaterials.
Cell culture: mPEG-HA can also be used in cell culture as a support for cell growth or as an additive to media.
Cross-linking, labeling, and imaging: Functional groups in mPEG-HA can be involved in cross-linking reactions, biomolecular labeling, and biological imaging.
Product technical advantage
SINOPEG offers high quality PEG derivatives with novel and diverse product structures, abundant substituting groups, and high end-group substitution rates.
High PEG functional group content - Content up to 99%
Functionalization of PEG is the most difficult of PEG products. The common problem of the main products on the market is that the functional group content is not high. And we master the modification technology, initiation system, unconventional precipitation method and system extraction method and other technologies and processes can easily produce high functional group content products. The functional group content of most products can reach 99%, which is much higher than the 90% or so of rivals.
High quality PEG molecular weight control -PDI <1.05
The single molecule chain of a polymer is usually composed of many small repeating units connected by polymerization. The design and control of the synthesis method has a crucial influence on the length of a single polymer segment and the similarity of the length of multiple polymer segments. Our PEG synthesis technology guarantees very good dispersion (PDI<1.05), while many other companies' products typically have PDI around 1.1.
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