1. Basic information of mPEG-VA
English name: mPEG-VA
Structural characteristics: The mPEG portion consists of a linear or branched polymer of repeated glycol units, with one end attached to a methoxy group and the other to a valerate group (-CH2CH2CH2CH2COOH).
Storage conditions: It is usually necessary to store at -20±5 ° C to ensure its stability and activity.
2. Functional group characteristics
The functional group of mPEG-VA mainly refers to its terminal valerate group (-CH2CH2CH2CH2COOH), which has the following properties:
Reactivity: The carboxyl group (-COOH) in the valerate group is reactive and can react with a variety of compounds, such as esterification and amidation. This allows mPEG-VA to be used as a linking or modifying molecule to build more complex biomolecular systems or material systems.
Biocompatibility: mPEG-VA has good biocompatibility due to the presence of the PEG part. This means that it does not trigger a significant immune response or rejection in living organisms, thus guaranteeing its safety for biomedical applications.
Water solubility: The PEG portion also gives mPEG-VA a good water solubility. This allows mPEG-VA to be stable in aqueous solutions and easily react or interact with other biomolecules.
3. Application field
Biopharmaceutical: Because of its good biocompatibility and water solubility, mPEG-VA is often used in the field of biopharmaceutical, such as drug modification and protein drug stabilization. By covalent bonding with protein drugs, mPEG-VA can reduce the immunogenicity of drugs and improve the stability and bioavailability of drugs.
Biomedical technology: In the field of biomedical technology, mPEG-VA can be used to prepare biomaterials such as hydrogels and microspheres. These biomaterials have broad application prospects in drug delivery and tissue engineering.
Nanotechnology: In the field of nanotechnology, mPEG-VA can be used as a surface modifier for nanoparticles to improve their stability and biocompatibility.
Product technical advantage
SINOPEG offers high quality PEG derivatives with novel and diverse product structures, abundant substituting groups, and high end-group substitution rates.
High PEG functional group content - Content up to 99%
Functionalization of PEG is the most difficult of PEG products. The common problem of the main products on the market is that the functional group content is not high. And we master the modification technology, initiation system, unconventional precipitation method and system extraction method and other technologies and processes can easily produce high functional group content products. The functional group content of most products can reach 99%, which is much higher than the 90% or so of rivals.
High quality PEG molecular weight control -PDI <1.05
The single molecule chain of a polymer is usually composed of many small repeating units connected by polymerization. The design and control of the synthesis method has a crucial influence on the length of a single polymer segment and the similarity of the length of multiple polymer segments. Our PEG synthesis technology guarantees very good dispersion (PDI<1.05), while many other companies' products typically have PDI around 1.1.
Relevant recommendation
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mPEG-NH2
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3-arm PEG-OH
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mPEG-CM
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3-arm PEG-NH2
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mPEG-SA
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3-arm PEG-CM
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mPEG-SH
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3-arm PEG-SH
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mPEG-pALD
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3-arm PEG-SC
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mPEG-MAL
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3-arm PEG-N3
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mPEG-SC
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3-arm PEG-NH2·HCl
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mPEG-NPC
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4-arm PEG-OH
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mPEG-SS
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4-arm PEG-NH2
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mPEG-N3
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4-arm PEG-CM
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mPEG-AA
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4-arm PEG-SA
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mPEG-MA
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4-arm PEG-SH
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mPEG-VS
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6-arm PEG-OH
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mPEG-NH2·HCl
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6-arm PEG-NH2
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2-arm PEG-OH
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6-arm PEG-CM
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2-arm PEG-COOH
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6-arm PEG-SA
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2-arm PEG-NHS
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6-arm PEG-SH
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2-arm PEG-MAL
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8-arm PEG-NH2
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2-arm PEG-NH2
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8-arm PEG-CM
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2-arm PEG-Acetal
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8-arm PEG-SA
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2-arm PEG-CHO
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8-arm PEG-SH
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2-arm PEG-N3
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8-arm PEG-pALD
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