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Insulin detemide side chains
January 9,2024.
Insulin is an important bioactive peptide hormone that plays a crucial role in regulating blood glucose and lipid metabolism. In order to improve the stability and bioactivity of insulin, scientists h...
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DLin-MC3-DMA is a synthetic lipid commonly used in the preparation of nanoparticles
January 4,2024.
DLin-MC3-DMA (1,2-dilinoleyloxy-3-dimethylaminopropane) is a synthetic lipid commonly used in the preparation of nanoparticles, particularly in gene and drug delivery systems. DLin-MC3-DMA belongs to ...
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Tirzepatide side chain
January 2,2024.
Tirzepatide side chain, as one of the notable biopharmaceuticals in recent years, has sparked a new wave of research in the field of medicine. Its unique molecular structure and potential clinical app...
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Drug discovery and development scheme for liver-targeting bridged nucleic acid antisense oligonucleotides
September 14,2022.
#ASOs #antisense oligonucleotide #GalNAc #drug delivery #ligand targeting Drug development scheme using the GalNAc conjugate, is better suited for selecting BNA-based ASOs, especially for ...
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PROTAC linker
January 22,2021.
PROTAC (proteolysis targeting chimeras) is a kind of dual functional molecules. The PROTAC molecule is composed of three parts: one end is a ligand molecule binding to the target protein to be degrade...
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Protein polyglycolization
September 3,2020.
The coupling of PEG to protein is also called protein polyglycolization, which is essentially a drug delivery technology. The coupling of activated peg with protein molecules can improve the three-dim...
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Sales of semaglutide increased by 152%!
August 18,2020.
According to statistics, the number of diabetes patients in the world has reached 425 million in 2017.It is estimated that the number of diabetes patients in the world will reach 629 million in 2045.D...
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Polyethylene glycol
August 7,2020.
Polyethylene glycol (PEG) is a hydrophilic and highly biocompatible polymer. In drug delivery, PEG can be used as a linker for antibody-drug conjugates (ADC) or as a surface coating for nanoparticles ...
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