1. Basic characteristics
Name: Amine-PEG4-Amine or NH₂-PEG4-NH₂
Molecular weight: ~264.3 g/mol (PEG4 part approximately 176 Da + two aminoethyl parts)
CAS number: Generally, there is no fixed CAS. Different suppliers may have different numbers
Properties: Colorless or pale yellow liquid (low molecular weight) or white solid (high molecular weight analogue)
Solubility: Readily soluble in water, methanol, DMSO and other polar solvents
2. Main applications
(1) Biological coupling
Protein/antibody modification: PEG modification is achieved through the reaction of amino groups with carboxyl groups (such as NHS esters).
Nucleic acid coupling: Used for synthesizing PEG-modified oligonucleotide probes to enhance stability and cell penetration.
(2) Drug delivery
Construction of degradable linker arms: For the coupling of small molecule drugs with antibodies (ADCs) or nanoparticles.
Enhance water solubility: Modify hydrophobic drugs to improve their biodistribution and pharmacokinetics.
(3) Materials Science
Surface functionalization: Modifying gold nanoparticles, quantum dots or polymer materials to introduce active amino groups.
Hydrogel crosslinking: As a crosslinking agent, it reacts with epoxy groups or acrylates to form a gel network.
Product: Various Kingds And Grades Of Such Monodispersed Are Readily Avaliable| SINOPEG
