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Home / Blog / ADC/PROTAC Linker | H2N-PEG2-CH2CH2NH2 | CAS#: 929-59-9 | SINOEPG
ADC/PROTAC Linker | H2N-PEG2-CH2CH2NH2 | CAS#: 929-59-9 | SINOEPG September 22,2025.
I. Basic Information

Chemical name: 1, 2-bis (2-aminoethoxy)ethane.

Molecular formula: C₆H₁₆N₂O₂.

Molecular weight: 148.2.

CAS Number: 929-59-9.



II. Structure and Properties

1. Structure: This compound consists of two amino groups (-NH₂) respectively connected to the two ends of a polyethylene glycol chain, with an ethylene glycol unit (-CH₂CH₂O-) in the middle.

2. Physical properties:

Appearance: Usually a colorless to pale yellow liquid.

Solubility: Readily soluble in water.

3. Chemical Properties: Amino groups have high reactivity and can participate in various chemical reactions, such as acylation, alkylation, condensation, etc.



III. Uses

1. Biomedical field:

Drug carriers: The amino terminus can bind to drug molecules and be used to prepare targeted drug carriers.

Biosensor: It can be used to build biosensors and detect biomolecules.

2. Field of Materials science:

Polymer synthesis: As a functional monomer, it is used to synthesize polymers with specific properties.

Surface modification: It is used to modify the surface of nanomaterials to improve their biocompatibility and stability.

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