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C12-200 (CAS: 1220890-25-4)
September 27,2024.
C12-200 cationic lipid is a unique lipid molecule with cationic properties. It consists of a hydrophobic tail and a positively charged hydrophilic head. This molecular structure enables C12-200 cation...
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Molecular Mechanisms and Processes of LNP-Mediated mRNA Transmembrane Delivery
March 7,2025.
Introduction Lipid nanoparticles (LNPs) represent the core technological platform for mRNA drug delivery, enabling efficient nucleic acid transport by mimicking cellular membrane structures. This arti...
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Berberine-Structure-Based Brain Targeting Breakthrough: BE-ST Nano Platform Overcomes Blood-Brain Barrier Challenges
July 21,2025.
The blood-brain barrier (BBB), a critical defense guarding the central nervous system, effectively blocks harmful substances but also severely impedes the entry of therapeutic drugs into the brain, co...
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Institute of Chemistry, Chinese Academy of Sciences: Cryo-induction Strategy Upgrades LNP Delivery
December 25,2025.
In the field of mRNA vaccines and nucleic acid therapies, lipid nanoparticles (LNPs) serve as the core carriers for efficient nucleic acid delivery, with lipid materials being key determinants of LNP ...
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