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Molecular Mechanisms and Processes of LNP-Mediated mRNA Transmembrane Delivery
March 7,2025.
Introduction Lipid nanoparticles (LNPs) represent the core technological platform for mRNA drug delivery, enabling efficient nucleic acid transport by mimicking cellular membrane structures. This arti...
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mPEG-N3 | SINOPEG peg derivative functional group
March 25,2025.
Chemical structure and properties 1. Chemical composition mPEG-N3 is a functionalized polyethylene glycol (PEG) derivative whose structure consists of two parts: Methoxy (-Och-₃) -modified PEG chain: ...
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mPEG-AA | SINOPEG peg derivative functional group
April 9,2025.
1. Definition and chemical structure mPEG-AA, full name mPEG-Acetic Acid is a linear mono-functional agglomerating glycol acid agent. Its chemical structure consists of the following two parts: Methox...
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mPEG-NCO | SINOPEG peg derivative functional group
April 21,2025.
mPEG-NCO (Methoxy Polyethylene Glycol Isocyanate) is a polyethylene glycol (PEG) derivative with an isocyanate (-NCO) active group at the end, and is widely used in fields such as biocoupling, drug de...
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mPEG-IAA | SINOPEG peg derivative functional group
April 21,2025.
mPEG-IAA (methoxy polyethylene glycol iodoacetamide, mPEG-Iodoacetamide) is a functionalized polyethylene glycol (PEG) derivative, which is widely used in biomedical research, drug delivery, molecular...
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Precision Targeting in Drug Delivery: Unleash the Power of DSPE-PEG-MAL
July 10,2025.
Achieving precise delivery of therapeutic agents to specific cells remains a cornerstone of modern medicine. Unlock new levels of precision in ligand-mediated drug delivery with DSPE-PEG-MAL, a versat...
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Berberine-Structure-Based Brain Targeting Breakthrough: BE-ST Nano Platform Overcomes Blood-Brain Barrier Challenges
July 21,2025.
The blood-brain barrier (BBB), a critical defense guarding the central nervous system, effectively blocks harmful substances but also severely impedes the entry of therapeutic drugs into the brain, co...
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Chemical Properties and Structural Analysis of DMG-PEG 2000
October 30,2025.
DMG-PEG 2000, chemically known as 1, 2-dimyrisyl-rac-glycerol-3-methoxy polyethylene glycol 2000, is a peG-modified lipid excipient that plays a crucial role in nanomedicine delivery systems. Its CAS ...
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The Application of DMG-PEG 2000 in mRNA Vaccine and Nucleic Acid Drug Delivery
October 30,2025.
In the field of biomedicine, especially in the booming mRNA vaccines and nucleic acid drugs in recent years, DMG-PEG 2000 plays an indispensable role. As one of the key components of the lipid nanopar...
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Customizable PEGylated Lipids
December 16,2025.
In modern materials science and biological applications, a class of highly flexible functional substances is increasingly becoming a key force driving technological breakthroughs—these are customizabl...
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Applications of Multi-Arm Polyethylene Glycol
December 23,2025.
Polyethylene glycol (PEG), as an important synthetic polymer, is widely used in pharmaceuticals and biomedicine due to its excellent biocompatibility, low toxicity, and superior solubility. In recent ...
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Institute of Chemistry, Chinese Academy of Sciences: Cryo-induction Strategy Upgrades LNP Delivery
December 25,2025.
In the field of mRNA vaccines and nucleic acid therapies, lipid nanoparticles (LNPs) serve as the core carriers for efficient nucleic acid delivery, with lipid materials being key determinants of LNP ...
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