Industrial Crops and Products. Volume 152, 15 September 2020, 112497
https://doi.org/10.1016/j.indcrop.2020.112497
Avermectin loaded carboxymethyl cellulose nanoparticles with stimuli-responsive and controlled release properties
Huaxin Zhu, Yue Shen, Jianxia Cui, Anqi wang, Ningjun Li, Chong Wang, Bo Cui, Changjiao Sun, Xiang Zhao, Chunxin Wang, Fei Gao, Shenshan Zhan, Liang Guo, Liang Zhang, Zhanghua Zeng, Yan Wang, Haixin Cui
Abstract
Polyethylene glycol (PEG) was introduced into carboxymethyl cellulose (CMC) to form hydrophilic chain of PEG-CMC. Avermectin (Avm) was grafted on the long chain of PEG-CMC by use of N, N-dicyclohexylcarbodiimide (DCC) as the dehydrant and 4-dimethylaminopyridine (DMAP) as the catalyst to form the amphiphilic molecule. Then the avermectin nanoparticles was prepared with esterase-responsive sustained release successfully through self-assembly. The size of nanoparticles was less than 400 nm. Avermectin loading was 8% and the degradation rate was less than 50 % under the xenon arc lamp for 72 h. Compared with avermectin technical, it showed an obvious anti-photodegradation advantage. Compared with commercially available water-dispersible granules (WDG), the avermectin nanoparticles had a smaller contact angle on the cucumber leaf surface and there was a significant difference. The toxicity test showed that the nanoparticles have a certain insecticidal effect on the larva of Hyphantria cunea and the sensitivity increased gradually over time.
Related products
Abbreviation: mPEG-CM
Name: Methoxypoly(ethylene glycol) carboxymethyl
For more product information, please contact us at:
US Tel: 1-844-782-5734
US Tel: 1-844-QUAL-PEG
CHN Tel: 400-918-9898
Email: sales@sinopeg.com
