Products
Home /

Intermediate of Anti-diabetic Drug

/

Insulin Detemir Intermediate

/Insulin Detemir Side Chain [Myr-OSu]

Insulin Detemir Side Chain [Myr-OSu]

Cas:1662688-20-1
Product No.: 06040005800


Product Name:Insulin Detemir Side Chain

CAS No.: 69888-86-4

Abbrevition:Myr-OSu

Purity: ≥98%

Package Size: 1g/bottle、10g/bottle、100g/bottle

Storage: Store at -20±5℃, keep dry.

research use only


Inquiry now
product Details

Insulin Detemir Side Chain


Marketed as the brand name product Levemir, insulin detemir has a duration of action of 16-24 hours allowing for once-daily dosing. Levemir is considered "basal insulin" as it provides low concentrations of background insulin that can keep blood sugar stable between meals or overnight.

 

Insulin detemir is produced using recombinant DNA technology in yeast cells. This insulin analogue has a 14-C fatty acid, myristic acid, bound to the lysine amino acid at position B29. The myristoyl side chain increases self-association and albumin binding. This along with slow systemic absorption from the injection site prolongs distribution of the hormone into tissues and results in a long duration of action.

 

License is required from license holder.

SINOPEG is pleased to offer this C-14 fatty acid for your R&D and clinic research.

 

Reference:

1. Hennige AM .,etc., Tissue selectivity of insulin detemir action in vivo. Diabetologia. 2006 Jun;49(6):1274-82. Epub 2006 Mar 29;


2. Kurtzhals P,.,etc.,: Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use. Diabetes. 2000 Jun;49(6):999-1005;


3. Sorensen AR, .,etc.,: Insulin detemir is a fully efficacious, low affinity agonist at the insulin receptor. Diabetes Obes Metab. 2010 Aug;12(8):665-73;


4. Wada T,.,etc.,: Characteristics of signalling properties mediated by long-acting insulin analogue glargine and detemir in target cells of insulin. Diabetes Res Clin Pract. 2008 Sep;81(3):269-77.


5. Chen X,.,etc.,: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.

Send a Message

You can contact us any way that is convenient for you. We are available 24/7 via fax, email or telephone.

If you have questions or suggestions, please leave us a message, we will reply you as soon as we can!

Related Products
N3-PEG4-CH2CH2CH2OH N3-PEG4-CH2CH2CH2OH Cas:2028281-87-8

N3-PEG4-CH2CH2CH2OH


Product Name:N3-PEG4-CH2CH2CH2OH

CAS No.:2028281-87-8

M.W:277.16

Storage:-18℃ for long term storage,avoid light

Purity:>95%

Appearance:White or Off-White Solid

N3-PEG8-CH2COOH N3-PEG8-CH2COOH Cas:1343472-07-0

N3-PEG8-CH2COOH


Product Name:N3-PEG8-CH2COOH

CAS No.:1343472-07-0

M.W:453.23

Storage:-18℃ for long term storage,avoid light

Purity:>95%

Appearance:White or Off-White Solid

COOH-PEG3-COOH COOH-PEG3-COOH Cas:31127-85-2

COOH-PEG3-COOH

Product Name:COOH-PEG3-COOH

CAS No.:31127-85-2

M.W:3294.298

Storage:-18℃ for long term storage,avoid light

Purity:>95%

Appearance:White or Off-White Solid

L-HO-Pal-Glu(OSu)-OH (S)-2-(15-carboxy-pentadecanoylamino)-pentanedioic acid 5-(2,5-dioxo-pyrrolidin-1-yl) ester [L-HO-Pal-Glu(OSu)-OH]

Cas:943586-12-7
Product No.:06040003100

Product Name: L-HO-Pal-Glu(OSu)-OH



Purity: ≥98%

Package Size: 1g/bottle10g/bottle100g/bottle

Storage: Store at -20±5℃, keep dry.

research use only

N-Succinimidyl myristate N-Succinimidyl myristate [Myr-OSu]

Cas:69888-86-4
Product No.: 06040003200

Product Name: Myr-OSu


Purity: ≥98%

Package Size: 1g/bottle10g/bottle100g/bottle

Storage: Store at -20±5℃, keep dry.

research use only

Propenyl-PEG-NH2 α-Propenyl-ω-amino poly(ethylene glycol) [Propenyl-PEG-NH2]

Propenyl-PEG-NH2


Product Name:α-Propenyl-ω-amino poly(ethylene glycol)

Abbreviation:Propenyl-PEG-NH2

Molecular Weight: 2KDa, 5KDa, 10KDa, 20KDa

Package Size: 1g/bottle、10g/bottle、100g/bottle

Storage: Store at -20±5℃, keep dry.

Egg yolk lecithin Egg yolk lecithin Cas:93685-90-6

Egg yolk lecithin


Product Name:Egg yolk lecithin

CAS No.:93685-90-6

Package Size: 1kg/bottle, 10kg/bottle,100kg/bottle,1t/bottle,10t/bottle

Storage:-18℃ for long term storage,avoid light

Purity:>95%


mPEG-P(BLG)40 Methoxypoly(ethylene glycol)-block-poly(benzyl-L-glutamate)

mPEG-P(BLG)40


Purity: ≥98%

Package Size: 1kg/bottle, 10kg/bottle,100kg/bottle,1t/bottle,10t/bottle

Storage: Store at -20±5℃, keep dry.

N3-PEG5-COOH N3-PEG5-COOH Cas:1425973-16-5

N3-PEG5-COOH


Product Name:N3-PEG5-COOH

CAS No.:1425973-16-5

M.W:300.27

Storage:-18℃ for long term storage,avoid light

Purity:>95%

Appearance:White or Off-White Solid

MA-PEG-NCO α-Methacryloyl-ω-isocyanato poly(ethylene glycol) [MA-PEG-NCO]

MA-PEG-NCO


Product Name:α-Methacryloyl-ω-isocyanato poly(ethylene glycol)

Abbreviation:MA-PEG-NCO

Molecular Weight: 2KDa, 5KDa, 10KDa, 20KDa

Package Size: 1g/bottle、10g/bottle、100g/bottle

Storage: Store at -20±5℃, keep dry.

N3-PEG4-CH2CH2CH2OH N3-PEG4-CH2CH2CH2OH Cas:2028281-87-8

N3-PEG4-CH2CH2CH2OH


Product Name:N3-PEG4-CH2CH2CH2OH

CAS No.:2028281-87-8

M.W:277.16

Storage:-18℃ for long term storage,avoid light

Purity:>95%

Appearance:White or Off-White Solid

N3-PEG8-CH2COOH N3-PEG8-CH2COOH Cas:1343472-07-0

N3-PEG8-CH2COOH


Product Name:N3-PEG8-CH2COOH

CAS No.:1343472-07-0

M.W:453.23

Storage:-18℃ for long term storage,avoid light

Purity:>95%

Appearance:White or Off-White Solid

COOH-PEG3-COOH COOH-PEG3-COOH Cas:31127-85-2

COOH-PEG3-COOH

Product Name:COOH-PEG3-COOH

CAS No.:31127-85-2

M.W:3294.298

Storage:-18℃ for long term storage,avoid light

Purity:>95%

Appearance:White or Off-White Solid

L-HO-Pal-Glu(OSu)-OH (S)-2-(15-carboxy-pentadecanoylamino)-pentanedioic acid 5-(2,5-dioxo-pyrrolidin-1-yl) ester [L-HO-Pal-Glu(OSu)-OH]

Cas:943586-12-7
Product No.:06040003100

Product Name: L-HO-Pal-Glu(OSu)-OH



Purity: ≥98%

Package Size: 1g/bottle10g/bottle100g/bottle

Storage: Store at -20±5℃, keep dry.

research use only

N-Succinimidyl myristate N-Succinimidyl myristate [Myr-OSu]

Cas:69888-86-4
Product No.: 06040003200

Product Name: Myr-OSu


Purity: ≥98%

Package Size: 1g/bottle10g/bottle100g/bottle

Storage: Store at -20±5℃, keep dry.

research use only

Propenyl-PEG-NH2 α-Propenyl-ω-amino poly(ethylene glycol) [Propenyl-PEG-NH2]

Propenyl-PEG-NH2


Product Name:α-Propenyl-ω-amino poly(ethylene glycol)

Abbreviation:Propenyl-PEG-NH2

Molecular Weight: 2KDa, 5KDa, 10KDa, 20KDa

Package Size: 1g/bottle、10g/bottle、100g/bottle

Storage: Store at -20±5℃, keep dry.

Copyright © XIAMEN SINOPEG BIOTECH CO., LTD. All Rights Reserved.

Home

Products

News

contact