Join Us at TIDES USA 2025 in San Diego!  Mark your calendars! TIDES USA 2025—the premier event for oligonucleotide and peptide therapeutics—is coming to San Diego, USA, on May 19, 2025.    Visit SINOPEG at Booth #613 to explore cutting-edge solutions in:    Custom PEG Derivatives (mPEG, heterobifunctional PEGs, branched PEGs)    Lipid Nanoparticles (LNPs) & Lipidoids for nucleic acid delivery    Innovative Linker Technologies & ADC Payloads Why Stop By?  Discuss your formulation challenges with our PEGylation experts  Discover high-purity excipients for mRNA, siRNA, and peptide therapies  Learn how our GMP-grade materials accelerate preclinical-to-commercial transitions Spotlight Case Study: Ask us about our role in developing temperature-stable LNP formulations for a global COVID-19 vaccine partner! Schedule a 1:1 Meeting: Avoid the crowds—reserve your private session today: sales@sinopeg.com Can't attend? Explore our solutions online: http://www.sinopeg.com Let's shape the future of oligonucleotide and peptide therapeutics together! See you at #613.  #TIDES2025 DrugDiscovery #LNPs #mRNA #PeptideTherapeutics #BiotechInnovation

Exciting Announcement! SINOPEG is thrilled to announce that we will be exhibiting at TIDES USA 2025, taking place May 19–22 at the Manchester Grand Hyatt San Diego! Join us at Booth #613 to explore how SINOPEG continues to drive innovation in oligonucleotide and peptide therapeutics. As a trusted partner in the industry, we specialize in delivering high-quality building blocks, advanced intermediates, and customized solutions to accelerate your drug discovery and development projects. Why Visit Us? Discover our cutting-edge portfolio of products and services. Discuss collaboration opportunities with our expert team. Learn how we support global partners in overcoming complex R&D challenges. TIDES USA is the premier event for oligonucleotide and peptide therapeutics, and we're eager to connect with industry leaders, researchers, and innovators shaping the future of biopharma. Let's explore synergies and unlock new possibilities together! Save the Date: May 19–22, 2025 Location: Manchester Grand Hyatt San Diego Find Us: Booth #613 Can't wait to meet you there? Drop us a message or comment below – let's start the conversation today!

Lipid nanoparticle (LNP) delivery systems are widely used in the fields of gene therapy and vaccines.However, to achieve effective gene delivery and vaccine delivery, not only suitable carriers and nucleic acids or antigens need to be selected, but also excipients for LNP delivery systems are needed.These excipients play a key role in stability, transparency, protective effect, and charge capacity. Firstly, stability is an important characteristic of excipients for LNP delivery systems.Excipients interact with lipid components, increasing the stability of LNP.For example, polyethylene glycol (PEG) is one of the commonly used excipients, which can form a stable layer of polymer by covering the surface of LNP.This polymer layer helps to reduce protein and cell adsorption and provides additional stability, thereby prolonging the circulation life of LNP. Secondly, transparency is an important factor to be considered when designing LNP delivery systems.Transparency can affect the preparation of LNP and the visualization of the internal structure.Therefore, excipients are usually selected for their characteristics of lower absorption and scattering of light to obtain clear imaging and accurate structural analysis. In addition, excipients for LNP delivery systems can also provide protection, protecting nucleic acids or antigens from degradation. For example, cholesterol is a common excipient that can be inserted into LNP to form a barrier that protects the nucleic acid or antigen.This protective layer can prevent the nucleic acid or antigen from being attacked by enzymes and help improve delivery efficiency and immune activation. In addition, charge is also an important characteristic of excipients.Charge can affect the interaction between LNP and target cells and delivery efficiency.For example, some excipients can regulate the charge state on the surface of LNP to improve its adsorption and cell uptake, thus improving delivery effect. In summary, excipients in LNP delivery systems play an important role in gene therapy and vaccine research.By selecting appropriate excipients, the stability, transparency, protective effect and charge of LNP can be optimized to achieve efficient gene delivery and vaccine delivery.Researchers will continue to develop new excipients to further improve the performance of LNP delivery systems and promote the development of gene therapy and vaccine research. Lipids that has been registered with DMF: DLin-MC3-DMA* SM-102 (HUO)* ALC-0315 (DHA)* DHA-1 (ALC-0315 analogue) mPEG-DMG-2K ALC-0159 (mPEG-DTA)* mPEG-DTA-1-2K (ALC-0159 analogue) DSPC DOPE DOTAP-Cl Cholesterol (Plant) Click here for more lipid products * This product is protected by third-party patents. We provide patent-compliant technical consultation and services, not the product itself.

Exciting News! SINOPEG's polyethylene glycol derivative project has won the championship in the manufacturing sector at the provincial level in Fujian, CHINA! SINOPEG stands out with outstanding technological innovation and remarkable R&D strength, becoming a shining star in the provincial manufacturing industry.   This honor is a strong demonstration of the company's scientific and technological strength and innovation capabilities, and it is the highest recognition of the company's continuous investment and exploration in the field of technology. SINOPEG has been committed to supplying high-quality polyethylene glycol derivatives to its peers, focusing on the research and development of new products and technologies related to polyethylene glycol derivatives, and has developed a series of patented and non-patented proprietary technologies related to polyethylene glycol derivatives and preparation processes. SINOPEG will continue to uphold the spirit of "independent research and development, daring to innovate", constantly pursuing excellence, challenging oneself, and striving to promote technological innovation, contributing more to the industry's development.   On the road ahead, we will demonstrate even greater strength!