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Molecular Mechanisms and Processes of LNP-Mediated mRNA Transmembrane Delivery
March 7,2025.
Introduction Lipid nanoparticles (LNPs) represent the core technological platform for mRNA drug delivery, enabling efficient nucleic acid transport by mimicking cellular membrane structures. This arti...
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mPEG-N3 | SINOPEG peg derivative functional group
March 25,2025.
Chemical structure and properties 1. Chemical composition mPEG-N3 is a functionalized polyethylene glycol (PEG) derivative whose structure consists of two parts: Methoxy (-Och-₃) -modified PEG chain: ...
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mPEG-AA | SINOPEG peg derivative functional group
April 9,2025.
1. Definition and chemical structure mPEG-AA, full name mPEG-Acetic Acid is a linear mono-functional agglomerating glycol acid agent. Its chemical structure consists of the following two parts: Methox...
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mPEG-NCO | SINOPEG peg derivative functional group
April 21,2025.
mPEG-NCO (Methoxy Polyethylene Glycol Isocyanate) is a polyethylene glycol (PEG) derivative with an isocyanate (-NCO) active group at the end, and is widely used in fields such as biocoupling, drug de...
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mPEG-IAA | SINOPEG peg derivative functional group
April 21,2025.
mPEG-IAA (methoxy polyethylene glycol iodoacetamide, mPEG-Iodoacetamide) is a functionalized polyethylene glycol (PEG) derivative, which is widely used in biomedical research, drug delivery, molecular...
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mPEG-OMs | SINOPEG peg derivative functional group
May 8,2025.
1. Chemical structure Molecular formula: CH₃O-(CH₂CH₂O)ₙ-CH₂CH₂ -OMS mPEG: methoxy polyethylene glycol (methoxy PEG), providing hydrophilicity and biocompatibility. OMs: mesylate (-OSO₂CH₃), as an act...
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Berberine-Structure-Based Brain Targeting Breakthrough: BE-ST Nano Platform Overcomes Blood-Brain Barrier Challenges
July 21,2025.
The blood-brain barrier (BBB), a critical defense guarding the central nervous system, effectively blocks harmful substances but also severely impedes the entry of therapeutic drugs into the brain, co...
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BIS-PEG21-NHS ESTER | CAS: 2221948-98-5 | sinopeg
September 5,2025.
BIS-PEG21-NHS ESTER is a very important heterogeneous bifunctional crosslinking agent in the fields of biocoupling chemistry and drug development. Its core value lies in its ability to simultaneously ...
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SINOPEG Novel PEG Lipid Delivery – A Solution for Pre-existing Anti-PEG Antibodies
November 17,2025.
Lipid Nanoparticles (LNPs), as one of the most successful nano-delivery carriers today, demonstrate exceptional capabilities in delivering cytotoxic chemotherapeutic drugs, antibiotics, and nucleic ac...
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Customizable PEGylated Lipids
December 16,2025.
In modern materials science and biological applications, a class of highly flexible functional substances is increasingly becoming a key force driving technological breakthroughs—these are customizabl...
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