News
  • Invitation Letter - CPHI Milan 2024 #6C92
    Invitation Letter - CPHI Milan 2024 #6C92 September 5,2024.
    We are pleased to invite you to join us at the CPHI Milan 2024, taking place on October 8-10, 2024, in Milan, Italy. SINOPEG will be showcasing our latest products and technologies, and we are eager to share our innovations and achievements. Event Details: Event Name: CPHI Milan 2024 Date: October 8-10, 2024 Location: Fiera Milano, Italy SINOPEG is committed to providing high-quality products and excellent services. This exhibition presents a fantastic opportunity for us to discuss potential collaborations, share industry insights, and present our innovative solutions. We warmly invite you to visit our booth #6C92, and we look forward to the opportunity to connect with you. Should you need any further information, please feel free to contact us. Thank you, and we hope to see you there!
    View More
  • Excipients for LNP Delivery Systems
    Excipients for LNP Delivery Systems January 22,2024.
    Lipid nanoparticle (LNP) delivery systems are widely used in the fields of gene therapy and vaccines.However, to achieve effective gene delivery and vaccine delivery, not only suitable carriers and nucleic acids or antigens need to be selected, but also excipients for LNP delivery systems are needed.These excipients play a key role in stability, transparency, protective effect, and charge capacity. Firstly, stability is an important characteristic of excipients for LNP delivery systems.Excipients interact with lipid components, increasing the stability of LNP.For example, polyethylene glycol (PEG) is one of the commonly used excipients, which can form a stable layer of polymer by covering the surface of LNP.This polymer layer helps to reduce protein and cell adsorption and provides additional stability, thereby prolonging the circulation life of LNP. Secondly, transparency is an important factor to be considered when designing LNP delivery systems.Transparency can affect the preparation of LNP and the visualization of the internal structure.Therefore, excipients are usually selected for their characteristics of lower absorption and scattering of light to obtain clear imaging and accurate structural analysis. In addition, excipients for LNP delivery systems can also provide protection, protecting nucleic acids or antigens from degradation. For example, cholesterol is a common excipient that can be inserted into LNP to form a barrier that protects the nucleic acid or antigen.This protective layer can prevent the nucleic acid or antigen from being attacked by enzymes and help improve delivery efficiency and immune activation. In addition, charge is also an important characteristic of excipients.Charge can affect the interaction between LNP and target cells and delivery efficiency.For example, some excipients can regulate the charge state on the surface of LNP to improve its adsorption and cell uptake, thus improving delivery effect. In summary, excipients in LNP delivery systems play an important role in gene therapy and vaccine research.By selecting appropriate excipients, the stability, transparency, protective effect and charge of LNP can be optimized to achieve efficient gene delivery and vaccine delivery.Researchers will continue to develop new excipients to further improve the performance of LNP delivery systems and promote the development of gene therapy and vaccine research. Lipids that has been registered with DMF: Ionizable Cationic Lipid DLin-MC3-DMA SM-102 (HUO) ALC-0315 (DHA) DHA-1 (ALC-0315 analogue) PEGylated Lipids mPEG-DMG-2K ALC-0159 (mPEG-DTA) mPEG-DTA-1-2K (ALC-0159 analogue) Neutral Phospholipid DSPC DOPE Sterol Lipids Cholesterol (Plant) Click here for more lipid products
    View More
first page 11 12 13 14 15 16 17 18 19 20 last page

A total of 20 pages

Copyright © XIAMEN SINOPEG BIOTECH CO., LTD. All Rights Reserved.

Home

Products

News

contact